Hi Pam a quick search on the 'net under hotel tyl prague will bring you loads up.
Here is one such search result - http://www.pragueholiday.cz/tyl-hotel-prague.php

Thanks Puddleduck. I had already looked on that site and enquired about booking. But they are a tour operator. They quoted a more expensive price than Destinia.com. The trouble with destinia is you have to pay the full amount on reservation which I don't really want to do. Destinia are quoting £63 per night for a double room. I want to book 2 rooms for 3 nights (£377).

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Mark

Thanks for your posts. Have now booked through Venere.com at £71 per night including breakfast.