For a flight under 12 hours, I just take a handbag with essentials in (purse, mobile, medication, a book, glasses, ipod) but this next one is a 21 hour flight to Australia overnight, so I'm taking a small suitcase within size regulations with a change of clothes for the next day, a jogging suit for the night, a squishee cushion, over night toiletries, and my laptop. When we're checked in, I'll be heading to WH smiths for some books and magazines