Hi Graham,
I took my boy 15, and girl 5 to Goa in January. It's a lovely time to goa, it's cooler in the evening. I'd say make sure you have ac. We went for a month.
Jabs - They are fine, we got all ours in the one session, phone your doctors first tell them where you are going, who is going and there ages/complications etc and they'll make sure they have all the correct dosage of injections ready.
Flight - Yeah long but give them game boys (on silent so they don't annoy the other passengers, We also took a portable dvd player (went cattle class with Monarch) and cd players with stories on for the little one. Colouring stuff and snacks (although we didn't need those as the food wasn't as bad as we had read about)
Malaria tablets - They weren't too much of a trawl to take, but both kids got a case of the runs and vomitting for 24 hours while climatising so they were ineffective (advice from the doctor) Doc told us to smother them in mossie repelent Osmodos (is the local one) did this no problems, no bites and the hotel we were in sprayed mossie repelent around the whole complex and in the rooms every night.
Both kids enjoyed it immensly, and never got bored, try and take them on a tour into the National parks - The Go Wild Tour is a 2 day condensed going to loads of different places. There is more about it in my report
here (thanks for the tip on URL's fiona

). The restaurant and shacks we went to were generally family run and they also had children it was a wonderful experience to watch your kids communicating with the local kids even though they didn't speak the same language. Give it a go I'm definately not going mainland europe and staying local because of the kids anymore. Take them, give them the experience of a lifetime.
Edit
just glad you managed to follow my explanation!
Fiona